well, ive read that and lifted this section.
Can the results of a baby rat test case, where they were fed extremely high doses by injection, have relevance to the effect of adult humans using comfrey? Noting that one comfrey leaf contains approximately one milligram of alkaloid in this particular test project, it is possible to give a similar dose level for man. As an average man is about 70kg it would be necessary to use the alkaloids from 19,880 leaves to produce a comparative dose level, and possible toxicity. As rat deaths occurred at levels equivalent to comfrey 28 times their body weight, it has been estimated that a man would need to consume 19,880 leaves, for a possible, similar effect. If humans were as vulnerable as baby rats to liver damage; and if these figures were less speculative, then it could be calculated that it would take 16 years to accumulate sufficient alkaloids to produce any detectable change in liver function. This would require eating, approximately, 100g of comfrey leaf, every day, based on each large leaf measuring an average 60cm, which would make 5- 6 large leaves, a day. Therefore, in order to reach the dose level at which the test showed that change in liver function occurred; it would take a man 48 years. Liver damage would result at around 150 years